NOD.B6-Idd5C57BL/6(R33)/GhjOrl

Status

Available to order

EMMA IDEM:01413
International strain nameNOD.B6-Idd5C57BL/6(R33)/GhjOrl
Alternative nameNOD.B6-Idd5-R33
Strain typeSpontaneous
Allele/Transgene symbolIdd5C57BL/6, Ctla4
Gene/Transgene symbolIdd5, Ctla4

Information from provider

ProviderHenri-Jean Garchon
Provider affiliationER70 CNRS et Unite 125 Inserm
Genetic informationNOD congenic strain with a proximal segment of chromosome 1 from C57BL/6 surrounding the Idd5 locus.
Phenotypic informationThis strain is NOT significantly protected against type 1 diabetes, despite having the Ctla4 gene of the B6 type.
Breeding history20 generations of backcrosses.
ReferencesNone available

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency / Orphanet_436159
MGI phenotypes (gene matching)
  • abnormal glucose homeostasis / MGI
  • periinsulitis / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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