NOD-Chr 17C57BL/6J/GhjCnrm
Status | Available to order |
EMMA ID | EM:01408 |
International strain name | NOD-Chr 17C57BL/6J/GhjCnrm |
Alternative name | NOD.B6-C17S |
Strain type | Spontaneous |
Allele/Transgene symbol | Chr 17C57BL/6J |
Gene/Transgene symbol | Chr 17 |
Information from provider
Provider | Henri-Jean Garchon |
Provider affiliation | ER70 CNRS et Unite 125 Inserm |
Genetic information | Non-obese diabetic (NOD) strain consomic with the Chr 17 substituted from the C57BL/6 strain. |
Phenotypic information | This line and the related lines, consomic, congenic and subcongenic for chromosome 17 and fragments of this chromosome, were derived to thoroughly investigate the role of the major histocompatibility complex (MHC) and MHC-linked genes in autoimmune predisposition, notably including type I diabetes (Idd1 and Idd16) loci and chronic autoimmune thyroiditis (Ceat1) locus, on the NOD background. |
Breeding history | 6 generations of backcrosses selected with the speed congenic approach, followed by sister-brother matings. |
References | None available |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
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