- abnormal vertebrae morphology / IMPC
- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal cranium morphology / IMPC
- abnormal spleen morphology / IMPC
- abnormal thymus morphology / IMPC
- enlarged thymus / IMPC
- abnormal skeletal muscle morphology / IMPC
- abnormal gait / IMPC
- male infertility / IMPC
- female infertility / IMPC
- abnormal skin morphology / IMPC
- abnormal digit morphology / IMPC
- increased circulating alanine transaminase level / IMPC
- decreased circulating alkaline phosphatase level / IMPC
- increased kidney weight / IMPC
- abnormal heart left ventricle morphology / IMPC
- abnormal vertebral arch morphology / IMPC
- increased circulating creatine kinase level / IMPC
- increased circulating lactate dehydrogenase level / IMPC
C57BL/6NCrl-Lrig3em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:13889 |
International strain name | C57BL/6NCrl-Lrig3em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Lrig3em1(IMPC)Ccpcz |
Gene/Transgene symbol | Lrig3 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal spleen morphology / IMPC
- increased circulating creatine kinase level / IMPC
- enlarged heart / IMPC
- abnormal gait / IMPC
- male infertility / IMPC
- enlarged thymus / IMPC
- abnormal skin morphology / IMPC
- increased circulating lactate dehydrogenase level / IMPC
- increased kidney weight / IMPC
- increased circulating alanine transaminase level / IMPC
- abnormal heart morphology / IMPC
- abnormal digit morphology / IMPC
- abnormal cranium morphology / IMPC
- abnormal thymus morphology / IMPC
- abnormal skeletal muscle morphology / IMPC
- female infertility / IMPC
- abnormal vertebral arch morphology / IMPC
- abnormal heart left ventricle morphology / IMPC
- decreased circulating alkaline phosphatase level / IMPC
- abnormal vertebrae morphology / IMPC
MGI phenotypes (gene matching)
- abnormal lateral semicircular canal morphology / MGI
- decreased circulating HDL cholesterol level / MGI
- abnormal craniofacial morphology / MGI
- short snout / MGI
- decreased body weight / MGI
- decreased body size / MGI
- circling / MGI
- increased heart rate / MGI
- decreased circulating insulin level / MGI
- increased systemic arterial blood pressure / MGI
- no phenotypic analysis / MGI
- decreased lateral semicircular canal size / MGI
- decreased posterior semicircular canal size / MGI
- decreased cardiac output / MGI
- decreased circulating glycerol level / MGI
- abnormal heart left ventricle morphology / MGI
- abnormal ear development / MGI
- head tossing / MGI
- hearing/vestibular/ear phenotype / MGI
- decreased cardiac stroke volume / MGI
- abnormal heart left ventricle weight / MGI
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