IMPC phenotypes (allele matching)
- increased red blood cell distribution width / IMPC
C57BL/6N-Il6raem1(IMPC)Wtsi/WtsiOulu
| Status | Available to order |
| EMMA ID | EM:13825 |
| International strain name | C57BL/6N-Il6raem1(IMPC)Wtsi/WtsiOulu |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Il6raem1(IMPC)Wtsi |
| Gene/Transgene symbol | Il6ra |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | University of Oulu, Oulu, Finland |
Disease and phenotype information
IMPC phenotypes (gene matching)
- increased red blood cell distribution width / IMPC
MGI phenotypes (gene matching)
- abnormal inflammatory response / MGI
- liver inflammation / MGI
- no abnormal phenotype detected / MGI
- decreased tumor growth/size / MGI
- increased hepatocyte apoptosis / MGI
- decreased hepatocyte proliferation / MGI
- decreased incidence of tumors by chemical induction / MGI
- abnormal wound healing / MGI
- decreased susceptibility to parasitic infection / MGI
- increased circulating aspartate transaminase level / MGI
- growth/size/body region phenotype / MGI
- abnormal CD4-positive, alpha-beta T cell physiology / MGI
- decreased circulating tumor necrosis factor level / MGI
- decreased circulating interleukin-1 beta level / MGI
- abnormal circulating serum amyloid protein level / MGI
- decreased susceptibility to parasitic infection induced morbidity/mortality / MGI