C57BL/6N-A^tm1Brd Jmjd1c^{tm1c(EUCOMM)Wtsi}/WtsiBiat

Status	Available to order
EMMA ID	EM:13799
International strain name	C57BL/6N-A^tm1Brd Jmjd1c^{tm1c(EUCOMM)Wtsi}/WtsiBiat
Alternative name	C57BL/6N-Atm1Brd Jmjd1c tm1a(EUCOMM)Wtsi/WtsiBiat
Strain type	Targeted Mutant Strains : Conditional mutation
Allele/Transgene symbol	Jmjd1c^{tm1c(EUCOMM)Wtsi}
Gene/Transgene symbol	Jmjd1c

Information from provider

Provider	Maik Dahlhoff
Provider affiliation	Department of Biomedical Sciences, University of Veterinary Medicine
Genetic information	This line originates from EMMA strain EM:07129, C57BL/6N A-tm1Brd Jmjd1c-tm1a(EUCOMM)Wtsi/WtsiIeg (EUCOMM ES clone EPD0628_4_H11), after breeding with a flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see this page at the IMPC portal.
Phenotypic information	Homozygous: no phenotype Heterozygous: no phenotype
Breeding history	n/a
References	None available
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	University of Veterinary Medicine, Vienna, Austria
Animals used for archiving	heterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (gene matching)

vertebral transformation / IMPC
abnormal iris morphology / IMPC
preweaning lethality, incomplete penetrance / IMPC
mydriasis / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6N-Atm1Brd Jmjd1ctm1c(EUCOMM)Wtsi/WtsiBiat