C57BL/6NCrl-Eif4g1em1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13721
International strain nameC57BL/6NCrl-Eif4g1em1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolEif4g1em1(IMPC)Hmgu
Gene/Transgene symbolEif4g1

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased bone mineral density / IMPC
  • abnormal vocalization / IMPC
  • abnormal retina vasculature morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • increased circulating chloride level / IMPC
  • decreased lean body mass / IMPC
  • decreased spleen weight / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased total body fat amount / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • increased total retina thickness / IMPC
  • increased fasting circulating glucose level / IMPC
IMPC phenotypes (gene matching)
  • increased circulating chloride level / IMPC
  • decreased spleen weight / IMPC
  • increased total retina thickness / IMPC
  • abnormal retina vasculature morphology / IMPC
  • abnormal vocalization / IMPC
  • increased fasting circulating glucose level / IMPC
  • increased total body fat amount / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • decreased lean body mass / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased bone mineral density / IMPC
  • increased circulating aspartate transaminase level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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