C57BL/6-Tg(rtetR-tetO-cre)40Mhz/Orl
| Status | Available to order |
| EMMA ID | EM:01372 |
| International strain name | C57BL/6-Tg(rtetR-tetO-cre)40Mhz/Orl |
| Alternative name | MeuCre40 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(rtetR-tetO-cre)40Mhz |
| Gene/Transgene symbol | Tg(rtetR-tetO-cre)40Mhz |
Information from provider
| Provider | Martin HOLZENBERGER |
| Provider affiliation | Université Pierre et Marie Curie, INSERM, U938, Hôpital Saint Antoine |
| Genetic information | Construct: a bidirectional CMV minimal promoter expressing wild-type cre recombinase cDNA on one side and rtTA on the other side. Although originally designed as auto-inducible by tetracycline, this transgenic strain is constitutively activated during early embryogenesis and can produce partial and mosaic loxP recombination from tri-lox alleles. |
| Phenotypic information | None |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.;Leneuve Patricia, Colnot Sabine, Hamard Ghislaine, Francis Fiona, Niwa-Kawakita Michiko, Giovannini Marco, Holzenberger Martin, ;2003;Nucleic acids research;31;e21; 12595570
- A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia.;Simon Camille, Chagraoui Jalila, Krosl Jana, Gendron Patrick, Wilhelm Brian, Lemieux Sébastien, Boucher Geneviève, Chagnon Pierre, Drouin Simon, Lambert Raphaëlle, Rondeau Claude, Bilodeau Annie, Lavallée Sylvie, Sauvageau Martin, Hébert Josée, Sauvageau Guy, ;2012;Genes & development;26;651-6; 22431509