IMPC phenotypes (gene matching)
B6NCrl;B6N-Atm1Brd Ddr1tm1c(EUCOMM)Hmgu/Orl
| Status | Available to order |
| EMMA ID | EM:13657 |
| Citation information | RRID:IMSR_EM:13657 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6NCrl;B6N-Atm1Brd Ddr1tm1c(EUCOMM)Hmgu/Orl |
| Alternative name | B6NCrl;B6N-A tm1Brd Ddr1 tm1c(EUCOMM)Hmgu /Orl |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Ddr1tm1c(EUCOMM)Hmgu |
| Gene/Transgene symbol | Ddr1 |
Information from provider
| Provider | Cécile FREMOND |
| Provider affiliation | CNRS-TAAM |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0812_6_B12. For further details on the construction of this clone see the relevant page (https://www.mousephenotype.org/data/alleles/MGI:99216/tm1a(EUCOMM)Hmgu) at the IMPC portal. The tm1a mice have been crossed with flp recombinase-expressing mice to obtain the tm1c allele. |
| Phenotypic information | Homozygous:Homozygous mice have not been generatedHeterozygous:Null |
| Breeding history | Rederived tm1a mice have been crossed with flp recombinase-expressing mice to obtain the tm1c allele. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6NCrl males |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cranium morphology / MGI
- abnormal mammary gland development / MGI
- decreased anxiety-related response / MGI
- hyperactivity / MGI
- failure of embryo implantation / MGI
- postnatal growth retardation / MGI
- abnormal lactation / MGI
- abnormal outer ear morphology / MGI
- abnormal bone mineralization / MGI
- increased urine protein level / MGI
- renal/urinary system phenotype / MGI
- homeostasis/metabolism phenotype / MGI
- abnormal podocyte slit diaphragm morphology / MGI
- abnormal mammary gland duct morphology / MGI
- abnormal renal tubule epithelium morphology / MGI
- increased mammary gland epithelial cell proliferation / MGI
- increased renal glomerulus basement membrane thickness / MGI
- erythrocyturia / MGI
- abnormal aorta collagen fibril morphology / MGI