C57BL/6NCrl-Ppp3cbem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:13578
Citation informationRRID:IMSR_EM:13578 

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International strain nameC57BL/6NCrl-Ppp3cbem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPpp3cbem1(IMPC)Ccpcz
Gene/Transgene symbolPpp3cb

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal kidney morphology / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • immune system phenotype / IMPC
  • decreased NK T cell number / IMPC
  • decreased CD4-positive, alpha-beta T cell number / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • decreased CD4-positive NK T cell number / IMPC
  • decreased memory-marker CD4-positive NK T cell number / IMPC
  • decreased T-helper cell number / IMPC
  • increased effector memory T-helper cell number / IMPC
IMPC phenotypes (gene matching)
  • decreased CD4-positive NK T cell number / IMPC
  • immune system phenotype / IMPC
  • increased effector memory T-helper cell number / IMPC
  • decreased T-helper cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • decreased memory-marker CD4-positive NK T cell number / IMPC
  • abnormal kidney morphology / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • decreased CD4-positive, alpha-beta T cell number / IMPC
  • decreased NK T cell number / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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