C57BL/6NCrl-Zfp280dem1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13577
International strain nameC57BL/6NCrl-Zfp280dem1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolZfp280dem1(IMPC)Hmgu
Gene/Transgene symbolZfp280d

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased locomotor activity / IMPC
  • abnormal startle reflex / IMPC
  • decreased startle reflex / IMPC
  • dilated heart left ventricle / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • decreased cardiac muscle contractility / IMPC
  • decreased heart rate / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
  • decreased prepulse inhibition / IMPC
  • prolonged QRS complex duration / IMPC
  • prolonged RR interval / IMPC
IMPC phenotypes (gene matching)
  • dilated heart left ventricle / IMPC
  • decreased prepulse inhibition / IMPC
  • decreased locomotor activity / IMPC
  • decreased startle reflex / IMPC
  • abnormal startle reflex / IMPC
  • prolonged RR interval / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • prolonged QRS complex duration / IMPC
  • decreased cardiac muscle contractility / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • decreased heart rate / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).