- impaired righting response / IMPC
- stereotypic behavior / IMPC
- decreased blood urea nitrogen level / IMPC
- persistence of hyaloid vascular system / IMPC
- decreased circulating amylase level / IMPC
- increased lean body mass / IMPC
- cataract / IMPC
- abnormal gait / IMPC
- increased mean platelet volume / IMPC
- trunk curl / IMPC
- increased leukocyte cell number / IMPC
- abnormal lens morphology / IMPC
C57BL/6N-Cybatm1c(EUCOMM)Wtsi/WtsiKieg
Status | Available to order |
EMMA ID | EM:13539 |
Citation information | RRID:IMSR_EM:13539 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6N-Cybatm1c(EUCOMM)Wtsi/WtsiKieg |
Alternative name | EPD0372_5_B08 |
Strain type | Targeted Mutant Strains : Targeted Conditional |
Allele/Transgene symbol | Cybatm1c(EUCOMM)Wtsi |
Gene/Transgene symbol | Cyba |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This line originates from EUCOMM ES clone EPD0372_5_B08, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Chronic granulomatous disease / Orphanet_379
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- impaired swimming / MGI
- impaired balance / MGI
- increased inflammatory response / MGI
- lung inflammation / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal neutrophil physiology / MGI
- absent otoliths / MGI
- absent linear vestibular evoked potential / MGI
- sepsis / MGI
- head tilt / MGI
- hearing/vestibular/ear phenotype / MGI
- abnormal intestinal goblet cell physiology / MGI