IMPC phenotypes (gene matching)
C57BL/6N-Kdm5bem2(IMPC)Wtsi/WtsiH
| Status | Available to order |
| EMMA ID | EM:13527 |
| Citation information | RRID:IMSR_EM:13527 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Kdm5bem2(IMPC)Wtsi/WtsiH |
| Alternative name | Kdm5bem2(IMPC)Wtsi (VAAE) |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Kdm5bem2(IMPC)Wtsi |
| Gene/Transgene symbol | Kdm5b |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | Kdm5bem2(IMPC)Wtsi. Inverted exon KI, reverted to WT via loxP71/loxP66 inversion |
| Phenotypic information | Homozygous:data not availableHeterozygous:data not available |
| Breeding history | Mosaic crossed with C57BL/6N then intercrossed |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive non-syndromic intellectual disability / Orphanet_88616
MGI phenotypes (gene matching)
- abnormal mammary gland development / MGI
- abnormal branching of the mammary ductal tree / MGI
- reduced female fertility / MGI
- female infertility / MGI
- premature death / MGI
- no phenotypic analysis / MGI
- decreased uterus weight / MGI
- decreased circulating estradiol level / MGI
- slow postnatal weight gain / MGI
- mortality/aging / MGI
- neonatal lethality, incomplete penetrance / MGI