C57BL/6N-Chd2tm1.2(IMPC)Wtsi/WtsiH

Status

Available to order

EMMA IDEM:13525
International strain nameC57BL/6N-Chd2tm1.2(IMPC)Wtsi/WtsiH
Alternative nameChd2tm1.2(IMPC)Wtsi (TCOQ)
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolChd2tm1.2(IMPC)Wtsi 
Gene/Transgene symbolChd2

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationChd2tm1.2(IMPC)Wtsi. KO first WT function activiated by cre excision of cassette. Post flp excision
Phenotypic informationHomozygous:
data not available

Heterozygous:
data not available
Breeding historyChimeras crossed with flp on C57BL/6N and crossed with C57BL/6N, then intercrossed
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • short tibia / IMPC
  • abnormal bone structure / IMPC
  • decreased prepulse inhibition / IMPC
  • decreased mean platelet volume / IMPC
  • increased grip strength / IMPC
  • decreased body length / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased hemoglobin content / IMPC
  • decreased erythrocyte cell number / IMPC
  • fibro-osseous lesion / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased bone mineral content / IMPC
  • hyperplasia / IMPC
  • abnormal sinus arrhythmia / IMPC
  • decreased bone mineral density / IMPC

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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