IMPC phenotypes (allele matching)
- increased circulating lipase level / IMPC
C57BL/6NCrl-Oma1em1(IMPC)Hmgu/Ieg
| Status | Available to order |
| EMMA ID | EM:13507 |
| International strain name | C57BL/6NCrl-Oma1em1(IMPC)Hmgu/Ieg |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Oma1em1(IMPC)Hmgu |
| Gene/Transgene symbol | Oma1 |
Information from provider
| Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References |
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Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
IMPC phenotypes (gene matching)
- increased circulating lipase level / IMPC
Literature references
- Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy.;Ahola Sofia, Pazurek Lilli A, Mayer Fiona, Lampe Philipp, Hermans Steffen, Becker Lore, Amarie Oana V, Fuchs Helmut, Gailus-Durner Valerie, de Angelis Martin Hrabe, Riedel Dietmar, Nolte Hendrik, Langer Thomas, ;2024;Science advances;10;eadp0443; 39093974