- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal spleen morphology / IMPC
- enlarged spleen / IMPC
- abnormal skin morphology / IMPC
- abnormal digit morphology / IMPC
- preweaning lethality, complete penetrance / IMPC
- embryonic lethality prior to organogenesis / IMPC
- embryonic lethality prior to tooth bud stage / IMPC
- decreased freezing behavior / IMPC
C57BL/6NCrl-Cog5em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:13502 |
Citation information | RRID:IMSR_EM:13502 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Cog5em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Cog5em1(IMPC)Ccpcz |
Gene/Transgene symbol | Cog5 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- COG5-CDG / Orphanet_263487
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal spleen morphology / IMPC
- decreased freezing behavior / IMPC
- abnormal skin morphology / IMPC
- embryonic lethality prior to organogenesis / IMPC
- enlarged heart / IMPC
- abnormal digit morphology / IMPC
- embryonic lethality prior to tooth bud stage / IMPC
- enlarged spleen / IMPC
- preweaning lethality, complete penetrance / IMPC
- abnormal heart morphology / IMPC
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