C57BL/6NCrl-Npeppsem1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13495
International strain nameC57BL/6NCrl-Npeppsem1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNpeppsem1(IMPC)Hmgu
Gene/Transgene symbolNpepps

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal retina morphology / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • abnormal tooth morphology / IMPC
  • decreased vertical activity / IMPC
  • decreased hemoglobin content / IMPC
  • decreased erythrocyte cell number / IMPC
  • thrombocytopenia / IMPC
  • abnormal bone structure / IMPC
  • increased lean body mass / IMPC
  • decreased total body fat amount / IMPC
  • increased grip strength / IMPC
  • decreased bone mineral content / IMPC
  • decreased total retina thickness / IMPC
  • absent teeth / IMPC
IMPC phenotypes (gene matching)
  • decreased vertical activity / IMPC
  • abnormal tooth morphology / IMPC
  • decreased locomotor activity / IMPC
  • decreased bone mineral content / IMPC
  • abnormal retina morphology / IMPC
  • absent teeth / IMPC
  • decreased hemoglobin content / IMPC
  • increased grip strength / IMPC
  • decreased total retina thickness / IMPC
  • thrombocytopenia / IMPC
  • decreased erythrocyte cell number / IMPC
  • increased lean body mass / IMPC
  • hyperactivity / IMPC
  • abnormal bone structure / IMPC
  • decreased total body fat amount / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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