C57BL/6NCrl-Plag1em1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13491
International strain nameC57BL/6NCrl-Plag1em1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPlag1em1(IMPC)Hmgu
Gene/Transgene symbolPlag1

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal head morphology / IMPC
  • abnormal snout morphology / IMPC
  • decreased body length / IMPC
  • decreased startle reflex / IMPC
  • short tibia / IMPC
  • abnormal bone structure / IMPC
  • abnormal auditory brainstem response / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased grip strength / IMPC
  • increased red blood cell distribution width / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
  • hyperplasia / IMPC
IMPC phenotypes (gene matching)
  • short tibia / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
  • abnormal snout morphology / IMPC
  • abnormal head morphology / IMPC
  • hyperplasia / IMPC
  • increased red blood cell distribution width / IMPC
  • increased grip strength / IMPC
  • abnormal bone structure / IMPC
  • decreased body length / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased startle reflex / IMPC
  • abnormal auditory brainstem response / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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