C57BL/6NCrl-Timp2^{em1(IMPC)Hmgu}/Ieg

Status	Available to order
EMMA ID	EM:13488
International strain name	C57BL/6NCrl-Timp2^{em1(IMPC)Hmgu}/Ieg
Alternative name
Strain type	Endonuclease-mediated
Allele/Transgene symbol	Timp2^{em1(IMPC)Hmgu}
Gene/Transgene symbol	Timp2

Information from provider

Provider	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliation	Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic information	This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic information	Potential phenotyping data in the IMPC portal
References	None available

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archiving	heterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)

abnormal hindlimb morphology / IMPC
abnormal body weight / IMPC
abnormal startle reflex / IMPC
decreased mean corpuscular volume / IMPC
single kidney / IMPC
increased follicular B cell number / IMPC
decreased grip strength / IMPC
decreased food intake / IMPC
decreased total retina thickness / IMPC
abnormal body fat mass / IMPC

IMPC phenotypes (gene matching)

decreased total retina thickness / IMPC
single kidney / IMPC
abnormal body fat mass / IMPC
decreased mean corpuscular volume / IMPC
abnormal startle reflex / IMPC
abnormal body weight / IMPC
abnormal hindlimb morphology / IMPC
decreased food intake / IMPC
increased follicular B cell number / IMPC
decreased grip strength / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6NCrl-Timp2em1(IMPC)Hmgu/Ieg