C57BL/6NCrl-Man2a1em1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13477
International strain nameC57BL/6NCrl-Man2a1em1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolMan2a1em1(IMPC)Hmgu
Gene/Transgene symbolMan2a1

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased circulating calcium level / IMPC
  • abnormal cecum morphology / IMPC
  • decreased mean corpuscular volume / IMPC
  • increased mean platelet volume / IMPC
  • abnormal vitreous body morphology / IMPC
  • increased heart weight / IMPC
  • decreased hemoglobin content / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • thrombocytopenia / IMPC
  • increased cardiac output / IMPC
  • decreased circulating iron level / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased circulating bilirubin level / IMPC
  • decreased blood urea nitrogen level / IMPC
  • increased circulating amylase level / IMPC
  • increased red blood cell distribution width / IMPC
IMPC phenotypes (gene matching)
  • decreased circulating calcium level / IMPC
  • decreased hemoglobin content / IMPC
  • increased circulating bilirubin level / IMPC
  • increased circulating amylase level / IMPC
  • thrombocytopenia / IMPC
  • increased cardiac output / IMPC
  • increased red blood cell distribution width / IMPC
  • abnormal vitreous body morphology / IMPC
  • increased heart weight / IMPC
  • decreased mean corpuscular volume / IMPC
  • abnormal cecum morphology / IMPC
  • decreased blood urea nitrogen level / IMPC
  • decreased circulating iron level / IMPC
  • increased mean platelet volume / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased circulating alkaline phosphatase level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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