- hyperactivity / IMPC
- decreased locomotor activity / IMPC
- decreased exploration in new environment / IMPC
- abnormal seminal vesicle morphology / IMPC
- increased hematocrit / IMPC
- decreased vertical activity / IMPC
- decreased lean body mass / IMPC
- increased total body fat amount / IMPC
- decreased bone mineral content / IMPC
- decreased respiratory quotient / IMPC
- decreased food intake / IMPC
C57BL/6NCrl-Ube3aem1(IMPC)Hmgu/Ieg
Status | Available to order |
EMMA ID | EM:13473 |
International strain name | C57BL/6NCrl-Ube3aem1(IMPC)Hmgu/Ieg |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Ube3aem1(IMPC)Hmgu |
Gene/Transgene symbol | Ube3a |
Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Angelman syndrome due to a point mutation / Orphanet_411511
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- hyperactivity / IMPC
- decreased locomotor activity / IMPC
- decreased vertical activity / IMPC
- decreased exploration in new environment / IMPC
- decreased lean body mass / IMPC
- increased total body fat amount / IMPC
- increased hematocrit / IMPC
- decreased food intake / IMPC
- decreased respiratory quotient / IMPC
- decreased bone mineral content / IMPC
- abnormal seminal vesicle morphology / IMPC
Information on how we integrate external resources can be found here
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