B6;129P2-Tg(Flt4)1Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:13465 |
| Citation information | RRID:IMSR_EM:13465 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Tg(Flt4)1Bld/Cnrm |
| Alternative name | TgVegfr3 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Flt4)1Bld |
| Gene/Transgene symbol | Tg(Flt4)1Bld |
Information from provider
| Provider | Antonio Baldini |
| Provider affiliation | Istituto di genetica e biofisica |
| Genetic information | The transgenic mouse line carries a single copy of a transgene containing a full length cDNA of the mouse Flt4 (FMS-like tyrosine kinase 4; or Vegfr3, vascular endothelial cell growth factor receptor 3) wild-type gene, generated by transfection of the transgene into mouse embryonic stem cells (ESC; E14Tg2A.4), followed by microinjection of the mESC into mouse blastocysts. |
| Phenotypic information | Homozygous:not generatedHeterozygous:none |
| Breeding history | Intercrossed with C57BL/6 and in sib-matings. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- A dual role for Tbx1 in cardiac lymphangiogenesis through genetic interaction with Vegfr3.;Martucciello Stefania, Turturo Maria Giuseppina, Bilio Marchesa, Cioffi Sara, Chen Li, Baldini Antonio, Illingworth Elizabeth, ;2020;FASEB journal : official publication of the Federation of American Societies for Experimental Biology;34;15062-15079; 32951265