C57BL/6N-Elac2^{tm1c(EUCOMM)Wtsi}/WtsiBiat

Status	Available to order
EMMA ID	EM:13457
Citation information	RRID:IMSR_EM:13457 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6N-Elac2^{tm1c(EUCOMM)Wtsi}/WtsiBiat
Alternative name	C57BL/6NTac-Elac2 tm1c(EUCOMM)Wtsi/WtsiBiat
Strain type	Targeted Mutant Strains : Conditional mutation
Allele/Transgene symbol	Elac2^{tm1c(EUCOMM)Wtsi}
Gene/Transgene symbol	Elac2

Information from provider

Provider	Maik Dahlhoff
Provider affiliation	Department of Biomedical Sciences, University of Veterinary Medicine
Genetic information	This line originates from EMMA strain EM:05966, C57BL/6NTac-Elac2^{tm1a(EUCOMM)Wtsi}/WtsiBiat (EUCOMM ES clone EPD0201_1_B07), after breeding with a flp recombinase-deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the relevant page at the IMPC portal (https://www.mousephenotype.org/data/genes/MGI:1890496#order).
Phenotypic information	Homozygous: No homozygous mice have been produced Heterozygous: No data available, no phenotype expected
Breeding history	1 backcross generation to C57BL/6N after flp-deleter breeding
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	not known
Immunocompromised	no

Information from EMMA

Archiving centre	University of Veterinary Medicine, Vienna, Austria
Animals used for archiving	heterozygous C57BL/6N males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Combined oxidative phosphorylation defect type 17 / Orphanet_369913

IMPC phenotypes (gene matching)

preweaning lethality, complete penetrance / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6N-Elac2tm1c(EUCOMM)Wtsi/WtsiBiat