IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
C57BL/6N-Elac2tm1c(EUCOMM)Wtsi/WtsiBiat
| Status | Available to order |
| EMMA ID | EM:13457 |
| International strain name | C57BL/6N-Elac2tm1c(EUCOMM)Wtsi/WtsiBiat |
| Alternative name | C57BL/6NTac-Elac2 tm1c(EUCOMM)Wtsi/WtsiBiat |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Elac2tm1c(EUCOMM)Wtsi |
| Gene/Transgene symbol | Elac2 |
Information from provider
| Provider | Maik Dahlhoff |
| Provider affiliation | Department of Biomedical Sciences, University of Veterinary Medicine |
| Genetic information | This line originates from EMMA strain EM:05966, C57BL/6NTac-Elac2tm1a(EUCOMM)Wtsi/WtsiBiat (EUCOMM ES clone EPD0201_1_B07), after breeding with a flp recombinase-deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the relevant page at the IMPC portal (https://www.mousephenotype.org/data/genes/MGI:1890496#order). |
| Phenotypic information | Homozygous:No homozygous mice have been producedHeterozygous:No data available, no phenotype expected |
| Breeding history | 1 backcross generation to C57BL/6N after flp-deleter breeding |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined oxidative phosphorylation defect type 17 / Orphanet_369913