IMPC phenotypes (allele matching)
C57BL/6NCrl-Gria1em1(IMPC)Hmgu/Ieg
| Status | Available to order |
| EMMA ID | EM:13442 |
| International strain name | C57BL/6NCrl-Gria1em1(IMPC)Hmgu/Ieg |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Gria1em1(IMPC)Hmgu |
| Gene/Transgene symbol | Gria1 |
Information from provider
| Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
IMPC phenotypes (gene matching)
- hyperactivity / IMPC
- increased circulating amylase level / IMPC
- decreased freezing behavior / IMPC
- decreased exploration in new environment / IMPC
- increased circulating serum albumin level / IMPC
- decreased prepulse inhibition / IMPC
- increased blood urea nitrogen level / IMPC
- impaired contextual conditioning behavior / IMPC
- increased circulating alkaline phosphatase level / IMPC
- abnormal freezing behavior / IMPC
- abnormal gait / IMPC
- impaired cued conditioning behavior / IMPC
- increased circulating iron level / IMPC
- increased mechanical nociceptive threshold / IMPC
- abnormal locomotor behavior / IMPC
- decreased bone mineral content / IMPC
- decreased vertical activity / IMPC
- hypoalgesia / IMPC
- decreased startle reflex / IMPC
MGI phenotypes (gene matching)
- abnormal spinal cord morphology / MGI
- decreased body size / MGI
- abnormal social investigation / MGI
- increased anxiety-related response / MGI
- decreased anxiety-related response / MGI
- abnormal locomotor behavior / MGI
- hyperactivity / MGI
- abnormal response to new environment / MGI
- increased exploration in new environment / MGI
- reduced long term potentiation / MGI
- absent long term depression / MGI
- impaired synaptic plasticity / MGI
- abnormal associative learning / MGI
- no abnormal phenotype detected / MGI
- abnormal long term potentiation / MGI
- abnormal sexual interaction / MGI
- abnormal emotion/affect behavior / MGI
- increased vertical activity / MGI
- abnormal nociception after inflammation / MGI
- no phenotypic analysis / MGI
- nervous system phenotype / MGI
- decreased aggression towards males / MGI
- abnormal serotonin level / MGI
- homeostasis/metabolism phenotype / MGI
- behavior/neurological phenotype / MGI
- increased blood urea nitrogen level / MGI
- decreased glycosylated hemoglobin level / MGI
- abnormal dendrite morphology / MGI
- abnormal long term spatial reference memory / MGI
- decreased chemical nociceptive threshold / MGI
- induced hyperactivity / MGI
- abnormal behavioral response to xenobiotic / MGI
- decreased behavioral withdrawal response / MGI
- reduced AMPA-mediated synaptic currents / MGI