C57BL/6NCrl-Pdcd6ipem1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13434
International strain nameC57BL/6NCrl-Pdcd6ipem1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPdcd6ipem1(IMPC)Hmgu
Gene/Transgene symbolPdcd6ip

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • enlarged lymph nodes / IMPC
  • decreased locomotor activity / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased grip strength / IMPC
  • decreased food intake / IMPC
IMPC phenotypes (gene matching)
  • abnormal kidney morphology / IMPC
  • decreased locomotor activity / IMPC
  • decreased food intake / IMPC
  • thick skin / IMPC
  • abnormal testis morphology / IMPC
  • enlarged lymph nodes / IMPC
  • small kidney / IMPC
  • decreased brain size / IMPC
  • small testis / IMPC
  • abnormal brain morphology / IMPC
  • decreased circulating bilirubin level / IMPC
  • abnormal skin morphology / IMPC
  • increased grip strength / IMPC
  • abnormal spleen morphology / IMPC
  • hypoplasia / IMPC
  • microphthalmia / IMPC
  • abnormal stomach morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal eye morphology / IMPC
  • hydrocephalus / IMPC
  • hydrocephaly / IMPC
  • decreased heart weight / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • increased mean platelet volume / IMPC
  • increased blood urea nitrogen level / IMPC
  • polycystic kidney / IMPC
  • decreased body length / IMPC
  • increased circulating HDL cholesterol level / IMPC
  • abnormal lung morphology / IMPC
  • enlarged seminal vesicle / IMPC
  • small heart / IMPC
  • atrophy / IMPC
  • abnormal heart morphology / IMPC
  • enlarged stomach / IMPC
  • decreased brain weight / IMPC
  • abnormal lymph node morphology / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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