C57BL/6N-Ndrg2em1(IMPC)Wtsi/WtsiCnrm

Status

Available to order

EMMA IDEM:13385
International strain nameC57BL/6N-Ndrg2em1(IMPC)Wtsi/WtsiCnrm
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNdrg2em1(IMPC)Wtsi
Gene/Transgene symbolNdrg2

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased inflammatory response / MGI
  • increased tumor incidence / MGI
  • increased T cell derived lymphoma incidence / MGI
  • premature death / MGI
  • abnormal thoracic vertebrae morphology / MGI
  • decreased neuron apoptosis / MGI
  • increased hepatocellular carcinoma incidence / MGI
  • abnormal glial cell physiology / MGI
  • lumbar vertebral transformation / MGI
  • sacral vertebral transformation / MGI
  • thoracic vertebral transformation / MGI
  • decreased susceptibility to injury / MGI
  • embryo phenotype / MGI
  • increased testis tumor incidence / MGI
  • decreased interleukin-6 secretion / MGI
  • increased lung carcinoma incidence / MGI
  • decreased survivor rate / MGI
  • abnormal astrocyte physiology / MGI
  • increased pancreas tumor incidence / MGI
  • increased brain tumor incidence / MGI
  • increased gastrointestinal tumor incidence / MGI
  • increased skin tumor incidence / MGI
  • abnormal microglial cell chemotaxis / MGI
  • increased fibroblast proliferation / MGI
  • decreased astrocyte number / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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