C57BL/6N-Myo5b^{em1(IMPC)Wtsi}/WtsiCnrm

Status	Available to order
EMMA ID	EM:13364
International strain name	C57BL/6N-Myo5b^{em1(IMPC)Wtsi}/WtsiCnrm
Alternative name
Strain type	Endonuclease-mediated
Allele/Transgene symbol	Myo5b^{em1(IMPC)Wtsi}
Gene/Transgene symbol	Myo5b

Information from provider

Provider	Wellcome Trust Sanger Institute
Provider affiliation	Wellcome Trust Sanger Institute
Genetic information	This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic information	Potential phenotyping data in the IMPC portal
References	None available

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Microvillus inclusion disease / Orphanet_2290
MYO5B-related progressive familial intrahepatic cholestasis / Orphanet_480491
Progressive familial intrahepatic cholestasis type 1 / Orphanet_79306

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

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C57BL/6N-Myo5bem1(IMPC)Wtsi/WtsiCnrm