C57BL/6NTac-Senp1em1(IMPC)H/H

Status

Available to order

EMMA IDEM:13354
International strain nameC57BL/6NTac-Senp1em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSenp1em1(IMPC)H
Gene/Transgene symbolSenp1

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • preweaning lethality, complete penetrance / IMPC
IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC
MGI phenotypes (gene matching)
  • abnormal erythropoiesis / MGI
  • abnormal vascular development / MGI
  • abnormal cell death / MGI
  • small liver / MGI
  • pale liver / MGI
  • abnormal liver physiology / MGI
  • anemia / MGI
  • prenatal lethality / MGI
  • abnormal megakaryocyte progenitor cell morphology / MGI
  • decreased erythrocyte cell number / MGI
  • no phenotypic analysis / MGI
  • abnormal vitelline vasculature morphology / MGI
  • decreased liver weight / MGI
  • pallor / MGI
  • enhanced coordination / MGI
  • decreased fetal size / MGI
  • hematopoietic system phenotype / MGI
  • abnormal hemoglobin content / MGI
  • abnormal granulocyte differentiation / MGI
  • abnormal monocyte differentiation / MGI
  • abnormal placental labyrinth vasculature morphology / MGI
  • decreased erythroid progenitor cell number / MGI
  • postnatal lethality, complete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • lethality throughout fetal growth and development, complete penetrance / MGI
  • lethality throughout fetal growth and development, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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