C57BL/6NTac-Sema3eem1(IMPC)H/H

Status

Available to order

EMMA IDEM:13334
International strain nameC57BL/6NTac-Sema3eem1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSema3eem1(IMPC)H
Gene/Transgene symbolSema3e

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased circulating phosphate level / IMPC
  • persistence of hyaloid vascular system / IMPC
  • irregularly shaped pupil / IMPC
  • abnormal retina morphology / IMPC
  • abnormal locomotor behavior / IMPC
  • abnormal placement of pupils / IMPC
  • impaired pupillary reflex / IMPC
  • abnormal retina blood vessel morphology / IMPC
IMPC phenotypes (gene matching)
  • persistence of hyaloid vascular system / IMPC
  • irregularly shaped pupil / IMPC
  • decreased circulating phosphate level / IMPC
  • impaired pupillary reflex / IMPC
  • abnormal placement of pupils / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • abnormal retina morphology / IMPC
  • abnormal locomotor behavior / IMPC
MGI phenotypes (gene matching)
  • abnormal motor neuron morphology / MGI
  • abnormal motor neuron innervation pattern / MGI
  • abnormal retina morphology / MGI
  • abnormal somite development / MGI
  • abnormal retinal vasculature morphology / MGI
  • nervous system phenotype / MGI
  • behavior/neurological phenotype / MGI
  • abnormal intersomitic vessel morphology / MGI
  • Bergmeister's papilla / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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