IMPC phenotypes (allele matching)
C57BL/6NTac-Cd74em1(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:13299 |
| International strain name | C57BL/6NTac-Cd74em1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Cd74em1(IMPC)H |
| Gene/Transgene symbol | Cd74 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased cell proliferation / MGI
- decreased body size / MGI
- arrested B cell differentiation / MGI
- decreased IgM level / MGI
- abnormal antigen presentation / MGI
- abnormal B cell differentiation / MGI
- abnormal professional antigen presenting cell physiology / MGI
- abnormal dendritic cell antigen presentation / MGI
- increased susceptibility to experimental autoimmune encephalomyelitis / MGI
- decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
- abnormal positive T cell selection / MGI
- decreased B cell number / MGI
- abnormal antigen presentation via MHC class II / MGI
- abnormal level of surface class II molecules / MGI
- defective assembly of class II molecules / MGI
- decreased B cell proliferation / MGI
- abnormal T cell proliferation / MGI
- decreased T cell proliferation / MGI
- cachexia / MGI
- increased T cell proliferation / MGI
- immune system phenotype / MGI
- hematopoietic system phenotype / MGI
- abnormal T-helper 1 physiology / MGI
- decreased susceptibility to type IV hypersensitivity reaction / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- increased immature B cell number / MGI
- decreased interferon-gamma secretion / MGI
- decreased interleukin-2 secretion / MGI
- abnormal lymph node cell ratio / MGI