IMPC phenotypes (allele matching)
C57BL/6NTac-Cd74em1(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:13299 |
| Citation information | RRID:IMSR_EM:13299 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Cd74em1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Cd74em1(IMPC)H |
| Gene/Transgene symbol | Cd74 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased cell proliferation / MGI
- decreased body size / MGI
- arrested B cell differentiation / MGI
- decreased IgM level / MGI
- abnormal antigen presentation / MGI
- abnormal B cell differentiation / MGI
- abnormal professional antigen presenting cell physiology / MGI
- abnormal dendritic cell antigen presentation / MGI
- increased susceptibility to experimental autoimmune encephalomyelitis / MGI
- decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
- abnormal positive T cell selection / MGI
- decreased B cell number / MGI
- abnormal antigen presentation via MHC class II / MGI
- abnormal level of surface class II molecules / MGI
- defective assembly of class II molecules / MGI
- decreased B cell proliferation / MGI
- abnormal T cell proliferation / MGI
- decreased T cell proliferation / MGI
- cachexia / MGI
- increased T cell proliferation / MGI
- immune system phenotype / MGI
- hematopoietic system phenotype / MGI
- abnormal T-helper 1 physiology / MGI
- decreased susceptibility to type IV hypersensitivity reaction / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- increased immature B cell number / MGI
- decreased interferon-gamma secretion / MGI
- decreased interleukin-2 secretion / MGI
- abnormal lymph node cell ratio / MGI