- abnormal spleen morphology / MGI
- demyelination / MGI
- decreased IgG level / MGI
- decreased IgM level / MGI
- brain inflammation / MGI
- abnormal T cell differentiation / MGI
- no abnormal phenotype detected / MGI
- abnormal lymph node T cell domain morphology / MGI
- abnormal double-positive T cell morphology / MGI
- increased susceptibility to viral infection / MGI
- abnormal CD4-positive, alpha beta T cell morphology / MGI
- decreased immunoglobulin level / MGI
- abnormal immune system organ morphology / MGI
- no phenotypic analysis / MGI
- absent CD4-positive, alpha beta T cells / MGI
- abnormal T cell subpopulation ratio / MGI
- abnormal bile salt level / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- abnormal CD8-positive, alpha beta T cell morphology / MGI
- decreased T cell number / MGI
- increased susceptibility to parasitic infection / MGI
- increased double-positive T cell number / MGI
- decreased double-positive T cell number / MGI
- decreased T cell proliferation / MGI
- immune system phenotype / MGI
- abnormal CD4-positive, alpha-beta T cell physiology / MGI
- increased CD4-positive, alpha beta T cell number / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- absent plasma cells / MGI
- impaired humoral immune response / MGI
C57BL/6NTac-Cd4em1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:13295 |
International strain name | C57BL/6NTac-Cd4em1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Cd4em1(IMPC)H |
Gene/Transgene symbol | Cd4 |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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