C57BL/6NTac-Gria2em1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:13293 |
International strain name | C57BL/6NTac-Gria2em1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Gria2em1(IMPC)H |
Gene/Transgene symbol | Gria2 |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- hippocampal neuron degeneration / MGI
- abnormal spinal cord morphology / MGI
- decreased body weight / MGI
- decreased body size / MGI
- hyperactivity / MGI
- jumpy / MGI
- hypoactivity / MGI
- impaired coordination / MGI
- decreased exploration in new environment / MGI
- abnormal grooming behavior / MGI
- decreased grooming behavior / MGI
- postnatal growth retardation / MGI
- absent long term depression / MGI
- impaired synaptic plasticity / MGI
- abnormal reflex / MGI
- abnormal touch/ nociception / MGI
- seizures / MGI
- abnormal motor capabilities/coordination/movement / MGI
- premature death / MGI
- abnormal nervous system electrophysiology / MGI
- abnormal emotion/affect behavior / MGI
- abnormal nociception after inflammation / MGI
- abnormal AMPA-mediated synaptic currents / MGI
- abnormal excitatory postsynaptic potential / MGI
- enhanced long term potentiation / MGI
- no phenotypic analysis / MGI
- abnormal response to novel object / MGI
- nervous system phenotype / MGI
- tonic-clonic seizures / MGI
- abnormal limb posture / MGI
- lethargy / MGI
- hearing/vestibular/ear phenotype / MGI
- hyperalgesia / MGI
- abnormal cell physiology / MGI
- increased susceptibility to neuronal excitotoxicity / MGI
- abnormal hippocampus CA3 region morphology / MGI
- decreased chemical nociceptive threshold / MGI
- paraparesis / MGI
- decreased grip strength / MGI
- enhanced AMPA-mediated synaptic currents / MGI
- postnatal lethality, complete penetrance / MGI
- postnatal lethality, incomplete penetrance / MGI
- abnormal circadian sleep/wake cycle / MGI
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