IMPC phenotypes (gene matching)
STOCK Slc7a11tm1c(EUCOMM)Wtsi/IcsOrl
| Status | Available to order |
| EMMA ID | EM:13218 |
| International strain name | STOCK Slc7a11tm1c(EUCOMM)Wtsi/IcsOrl |
| Alternative name | STOCK Slc7a11 tm1c(EUCOMM)Wtsi/IcsOrl |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Slc7a11tm1c(EUCOMM)Wtsi |
| Gene/Transgene symbol | Slc7a11 |
Information from provider
| Provider | Cécile FREMOND |
| Provider affiliation | CNRS-TAAM |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0508_3_E02. For further details on the construction of this clone see the page at the IMPC portal. The tm1a mice have been crossed with flp recombinase-expressing mice (EM:05490, C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics) to obtain the tm1c allele. |
| Phenotypic information | Homozygous:Homozygous mice have not been generatedHeterozygous:Null |
| Breeding history | Rederived tm1a mice have been crossed with flp recombinase-expressing mice to obtain the line carrying the tm1c allele. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cell death / MGI
- diluted coat color / MGI
- abnormal dendritic cell physiology / MGI
- abnormal macrophage physiology / MGI
- increased incidence of tumors by chemical induction / MGI
- decreased platelet serotonin level / MGI
- abnormal circulating amino acid level / MGI
- immune system phenotype / MGI
- increased bleeding time / MGI
- decreased fibroblast proliferation / MGI
- increased circulating cysteine level / MGI