B6;CBA-Tg(Sf1-Hoxb9)52Aswn/H
| Status | Available to order |
| EMMA ID | EM:13203 |
| International strain name | B6;CBA-Tg(Sf1-Hoxb9)52Aswn/H |
| Alternative name | Sf1- Hoxb9 (BAC52) |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Sf1-Hoxb9)52Aswn |
| Gene/Transgene symbol | Tg(Sf1-Hoxb9)52Aswn |
Information from provider
| Provider | Amanda Swain |
| Provider affiliation | Institute of Cancer Research |
| Genetic information | Mouse BAC transgene containing Sf1 locus with mouse Hoxb9 gene cDNA, plus rabbit beta globin polyadenylation inserted in the 5' untranslated region. |
| Phenotypic information | Homozygous:Homozygous animals have not been characterised.Heterozygous:Transgenic adrenals have a larger X zone |
| Breeding history | Crossed to either non-transgenic littermates or C57BL/6. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours.;Francis Jeffrey C, Gardiner Jennifer R, Renaud Yoan, Chauhan Ritika, Weinstein Yacob, Gomez-Sanchez Celso, Lefrançois-Martinez Anne-Marie, Bertherat Jérôme, Val Pierre, Swain Amanda, ;2021;British journal of cancer;124;805-816; 33214683