C57BL/6N-Bmxtm1c(EUCOMM)Wtsi/Oulu

Status

Available to order

EMMA IDEM:13146
International strain nameC57BL/6N-Bmxtm1c(EUCOMM)Wtsi/Oulu
Alternative nameBmx-LoxP
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolBmxtm1c(EUCOMM)Wtsi
Gene/Transgene symbolBmx

Information from provider

ProviderKari Alitalo
Provider affiliationTranslational Cancer Medicine, University of Helsinki
Genetic informationMouse model carrying the Bmx gene flanked by loxP sites to enable cre recombinase-induced knock-out.
Phenotypic informationHomozygous:
No phenotype for homozygous mice, as gene is functional prior to cre-induced recombination.

Heterozygous:
No phenotype for homozygous mice, as gene is functional prior to cre-induced recombination.
Breeding historyC57BL/6NTac-Bmxtm1a(EUCOMM)Wtsi/IcsOrl mice (EMMA strain ID EM:07672; EMMA request ID:6319) were crossed with flp recombinase-expressing mice to have conditional Bmx knock-out (tm1c). The flp recombinase was bred out after tm1c conversion.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreUniversity of Oulu, Oulu, Finland
Animals used for archivingheterozygous C57BL/6N, wild-type C57BL/6NCrl
Stage of embryos2-cell

Disease and phenotype information

MGI phenotypes (gene matching)
  • no abnormal phenotype detected / MGI
  • decreased susceptibility to induced arthritis / MGI
  • skeleton phenotype / MGI

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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