C57BL/6NCrl-Tnfsf15em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:13135
International strain nameC57BL/6NCrl-Tnfsf15em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolTnfsf15em1(IMPC)Ccpcz
Gene/Transgene symbolTnfsf15

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased IgG level / MGI
  • decreased susceptibility to induced arthritis / MGI
  • decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
  • decreased B cell number / MGI
  • decreased T cell number / MGI
  • immune system phenotype / MGI
  • increased NK cell number / MGI
  • decreased plasma cell number / MGI
  • lymph node hypoplasia / MGI
  • abnormal dendritic cell differentiation / MGI
  • decreased germinal center B cell number / MGI
  • decreased IgG2a level / MGI
  • decreased IgG2b level / MGI
  • decreased T follicular helper cell number / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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