C57BL/6NCrl-Fbxl3em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:13129
Citation informationRRID:IMSR_EM:13129 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Fbxl3em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFbxl3em1(IMPC)Ccpcz
Gene/Transgene symbolFbxl3

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal skeletal muscle morphology / IMPC
  • abnormal testis morphology / IMPC
  • enlarged testis / IMPC
  • abnormal retina morphology / IMPC
  • hydrocephaly / IMPC
  • abnormal skin morphology / IMPC
  • abnormal brain morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased circulating chloride level / IMPC
  • abnormal duodenum morphology / IMPC
  • decreased liver weight / IMPC
  • decreased lean body mass / IMPC
  • decreased spleen weight / IMPC
  • decreased circulating total protein level / IMPC
  • decreased effector memory T-helper cell number / IMPC
IMPC phenotypes (gene matching)
  • increased circulating chloride level / IMPC
  • abnormal spleen morphology / IMPC
  • decreased spleen weight / IMPC
  • decreased erythrocyte cell number / IMPC
  • abnormal skin morphology / IMPC
  • abnormal retina morphology / IMPC
  • abnormal brain morphology / IMPC
  • abnormal duodenum morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • decreased circulating total protein level / IMPC
  • increased lean body mass / IMPC
  • decreased effector memory T-helper cell number / IMPC
  • enlarged heart / IMPC
  • abnormal heart morphology / IMPC
  • abnormal skeletal muscle morphology / IMPC
  • enlarged testis / IMPC
  • abnormal testis morphology / IMPC
  • decreased lean body mass / IMPC
  • hydrocephaly / IMPC
  • decreased liver weight / IMPC
MGI phenotypes (gene matching)
  • abnormal hypothalamus physiology / MGI
  • abnormal circadian behavior / MGI
  • prolonged circadian behavior period / MGI
  • delayed circadian behavior phase / MGI
  • abnormal circardian behavior entrainment / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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