B6.Cg-Tg(Scgb1a1-cre)1Vart/Flmg
| Status | Available to order |
| EMMA ID | EM:13121 |
| Citation information | RRID:IMSR_EM:13121 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Scgb1a1-cre)1Vart/Flmg |
| Alternative name | B6-Tg(Scgb1a1-cre)1Vart/Flmg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Scgb1a1-cre)1Vart |
| Gene/Transgene symbol | Tg(Scgb1a1-cre)1Vart |
Information from provider
| Provider | Vassilis Aidinis |
| Provider affiliation | BioInnovation, BSRC |
| Genetic information | This transgene contains the cDNA encoding cre recombinase under control of the promoter from the rat secretoglobin, family 1A, member 1 gene (Clara cell 10 kD or CC10), which directs expression in Clara cells of the pulmonary epithelium. |
| Phenotypic information | Homozygous:No overt phenotypeHeterozygous:No overt phenotype |
| Breeding history | This mouse was generated in a B6;CBA mixed background and has now been back-crossed into pure C57BL/6 background. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | Morula |
Literature references
- Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.;Oikonomou Nikos, Mouratis Marios-Angelos, Tzouvelekis Argyris, Kaffe Eleanna, Valavanis Christos, Vilaras George, Karameris Andreas, Prestwich Glenn D, Bouros Demosthenes, Aidinis Vassilis, ;2012;American journal of respiratory cell and molecular biology;47;566-74; 22744859