- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal spleen morphology / IMPC
- abnormal skeletal muscle morphology / IMPC
- abnormal uterus morphology / IMPC
- abnormal skin morphology / IMPC
- abnormal eye morphology / IMPC
- abnormal digit morphology / IMPC
- abnormal kidney morphology / IMPC
- decreased lean body mass / IMPC
- decreased NK cell number / IMPC
- hydrometra / IMPC
- decreased effector memory T-helper cell number / IMPC
C57BL/6NCrl-Flt3em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:13110 |
Citation information | RRID:IMSR_EM:13110 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Flt3em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Flt3em1(IMPC)Ccpcz |
Gene/Transgene symbol | Flt3 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Acute myeloblastic leukemia with maturation / Orphanet_98834
- Acute myeloid leukemia with minimal differentiation / Orphanet_98832
- Acute myeloblastic leukemia without maturation / Orphanet_98833
- Mixed phenotype acute leukemia / Orphanet_530995
- Precursor B-cell acute lymphoblastic leukemia / Orphanet_99860
- Precursor T-cell acute lymphoblastic leukemia / Orphanet_99861
- B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality / Orphanet_585877
- Mixed phenotype acute leukemia with t(v;11q23.3) / Orphanet_589595
- Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2) / Orphanet_589534
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- hydrometra / IMPC
- decreased lean body mass / IMPC
- abnormal kidney morphology / IMPC
- abnormal spleen morphology / IMPC
- decreased NK cell number / IMPC
- abnormal heart morphology / IMPC
- decreased effector memory T-helper cell number / IMPC
- abnormal eye morphology / IMPC
- abnormal skeletal muscle morphology / IMPC
- abnormal uterus morphology / IMPC
- enlarged heart / IMPC
- abnormal skin morphology / IMPC
- abnormal digit morphology / IMPC
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