- decreased mast cell number / MGI
- altered response to myocardial infarction / MGI
- impaired hematopoiesis / MGI
- lung inflammation / MGI
- decreased airway responsiveness / MGI
- decreased susceptibility to viral infection / MGI
- decreased susceptibility to bacterial infection / MGI
- abnormal macrophage physiology / MGI
- abnormal neutrophil physiology / MGI
- granulomatous inflammation / MGI
- glomerulonephritis / MGI
- increased urine protein level / MGI
- abnormal leukocyte adhesion / MGI
- increased length of allograft survival / MGI
- decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
- increased susceptibility to parasitic infection / MGI
- glomerulosclerosis / MGI
- abnormal renal glomerulus morphology / MGI
- immune system phenotype / MGI
- increased susceptibility to fungal infection / MGI
- increased blood urea nitrogen level / MGI
- decreased susceptibility to type III hypersensitivity reaction / MGI
- increased susceptibility to type IV hypersensitivity reaction / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- decreased CD8-positive, alpha-beta T cell number / MGI
- abnormal Kupffer cell morphology / MGI
- increased IgG2a level / MGI
- increased tumor necrosis factor secretion / MGI
- decreased tumor necrosis factor secretion / MGI
- increased interferon-gamma secretion / MGI
- decreased circulating interferon-gamma level / MGI
- decreased interleukin-10 secretion / MGI
- increased interleukin-12 secretion / MGI
- decreased interleukin-13 secretion / MGI
- impaired neutrophil recruitment / MGI
- abnormal chemokine secretion / MGI
- cecum inflammation / MGI
- decreased susceptibility to bacterial infection induced morbidity/mortality / MGI
- abnormal cellular extravasation / MGI
- abnormal circulating chemokine level / MGI
- increased macrophage nitric oxide production / MGI
- glomerular crescent / MGI
C57BL/6NCrl-Ccr1em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:13051 |
International strain name | C57BL/6NCrl-Ccr1em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Ccr1em1(IMPC)Ccpcz |
Gene/Transgene symbol | Ccr1 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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