IMPC phenotypes (gene matching)
- increased exploration in new environment / IMPC
C57BL/6J-Cntnap2em3H/H
| Status | Available to order |
| EMMA ID | EM:13027 |
| Citation information | RRID:IMSR_EM:13027 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Cntnap2em3H/H |
| Alternative name | CNTNAP2-FLOX-EM3-B6 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Cntnap2em3H |
| Gene/Transgene symbol | Cntnap2 |
Information from provider
| Provider | MRC-Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:UnknownHeterozygous:None |
| Breeding history | Co-isogenic on original background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Pitt-Hopkins-like syndrome / Orphanet_221150
- Cortical dysplasia-focal epilepsy syndrome / Orphanet_163681
MGI phenotypes (gene matching)
- abnormal corpus callosum morphology / MGI
- decreased body size / MGI
- social withdrawal / MGI
- hyperactivity / MGI
- increased stereotypic behavior / MGI
- increased grooming behavior / MGI
- abnormal nest building behavior / MGI
- abnormal motor coordination/balance / MGI
- abnormal olfaction / MGI
- seizures / MGI
- astrocytosis / MGI
- abnormal response to novel odor / MGI
- nervous system phenotype / MGI
- decreased thermal nociceptive threshold / MGI
- abnormal brain interneuron morphology / MGI
- abnormal neuron physiology / MGI
- abnormal brain wave pattern / MGI
- behavior/neurological phenotype / MGI
- abnormal neuronal migration / MGI
- environmentally induced seizures / MGI
- cognitive inflexibility / MGI
- abnormal inhibitory learning / MGI
- decreased vocalization / MGI