C57BL/6NTac-Prdm8em1H/H

Status

Available to order

EMMA IDEM:13023
Citation informationRRID:IMSR_EM:13023 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Prdm8em1H/H
Alternative namePrdm8-FLOX-EM1-B6N
Strain typeEndonuclease-mediated
Allele/Transgene symbolPrdm8em1H
Gene/Transgene symbolPrdm8

Information from provider

Provider MRC-Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
Unkown at this stage - are breeding homs currently

Heterozygous:
None
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • increased heart rate / IMPC
  • increased circulating sodium level / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal retina morphology / IMPC
  • hyperactivity / IMPC
  • impaired glucose tolerance / IMPC
  • decreased locomotor activity / IMPC
  • abnormal tooth morphology / IMPC
  • decreased body weight / IMPC
  • increased prepulse inhibition / IMPC
  • increased freezing behavior / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • increased airway resistance / IMPC
  • small heart / IMPC
  • small spleen / IMPC
  • abnormal inspiratory capacity / IMPC
  • abnormal uterus morphology / IMPC
  • abnormal heart morphology / IMPC
  • increased anxiety-related response / IMPC
  • enlarged uterus / IMPC
  • increased lung elastance / IMPC
MGI phenotypes (gene matching)
  • skin lesions / MGI
  • excessive scratching / MGI
  • abnormal motor coordination/balance / MGI
  • absent corpus callosum / MGI
  • abnormal axon guidance / MGI
  • nervous system phenotype / MGI
  • absent hippocampal commissure / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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