C57BL/6NTac-Pde2a^em3H/H

Status	Available to order
EMMA ID	EM:13018
International strain name	C57BL/6NTac-Pde2a^em3H/H
Alternative name	Pde2a-D479G-EM3-B6N
Strain type	Endonuclease-mediated
Allele/Transgene symbol	Pde2a^em3H
Gene/Transgene symbol	Pde2a

Information from provider

Provider	MRC-Harwell
Provider affiliation	Mary Lyon Centre at MRC Harwell
Genetic information	For detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic information	Homozygous: Not known Heterozygous: None reported
Breeding history	Co-isogenic on original background
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	not known

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Infantile convulsions and choreoathetosis / Orphanet_31709

IMPC phenotypes (gene matching)

increased heart weight / IMPC
increased neutrophil cell number / IMPC
preweaning lethality, complete penetrance / IMPC
increased circulating bilirubin level / IMPC

MGI phenotypes (gene matching)

lethality throughout fetal growth and development, complete penetrance / MGI
preweaning lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6NTac-Pde2aem3H/H