IMPC phenotypes (gene matching)
B6;129-Tmsb4xtm1Prri/H
| Status | Available to order |
| EMMA ID | EM:01301 |
| Citation information | RRID:IMSR_EM:01301 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Tmsb4xtm1Prri/H |
| Alternative name | Tmsb4x |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Tmsb4xtm1Prri |
| Gene/Transgene symbol | Tmsb4x |
Information from provider
| Provider | Martin Turner |
| Provider affiliation | Babraham Institute |
| Genetic information | In this knock-out line B-lymphocyte development is impaired. |
| Phenotypic information | Impairment of B-lymphocyte development and immune deficient. |
| References |
|
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (allele matching)
- abnormal blood vessel morphology / MGI
- internal hemorrhage / MGI
- intracranial hemorrhage / MGI
- thin myocardium / MGI
- abnormal arteriole morphology / MGI
- hemopericardium / MGI
- vision/eye phenotype / MGI
- heart hemorrhage / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- abnormal vascular smooth muscle development / MGI
MGI phenotypes (gene matching)
- abnormal blood vessel morphology / MGI
- internal hemorrhage / MGI
- intracranial hemorrhage / MGI
- no abnormal phenotype detected / MGI
- thin myocardium / MGI
- abnormal arteriole morphology / MGI
- hemopericardium / MGI
- cardiovascular system phenotype / MGI
- vision/eye phenotype / MGI
- heart hemorrhage / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- abnormal vascular smooth muscle development / MGI
Literature references
- Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.;Rossdeutsch Alex, Smart Nicola, Dubé Karina N, Turner Martin, Riley Paul R, ;2012;Circulation research;111;e89-102; 22723298