B6J.129S2-Ncor1^tm1.2Ics/Ics

Status	Available to order
EMMA ID	EM:12998
International strain name	B6J.129S2-Ncor1^tm1.2Ics/Ics
Alternative name	Ncor1 KO
Strain type	Targeted Mutant Strains : Knock-out
Allele/Transgene symbol	Ncor1^tm1.2Ics
Gene/Transgene symbol	Ncor1

Information from provider

Provider	ICS, Institut Clinique de la Souris
Provider affiliation	ICS, Institut Clinique de la Souris
Genetic information	Exon 11 was flanked by loxP sites. An FRT site remains in intron from removal of the selection cassette.
Phenotypic information	Homozygous: not known Heterozygous: not known
Breeding history	7 backcross generations to C57BL/6J
References	NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.;Yamamoto Hiroyasu, Williams Evan G, Mouchiroud Laurent, Cantó Carles, Fan Weiwei, Downes Michael, Héligon Christophe, Barish Grant D, Desvergne Béatrice, Evans Ronald M, Schoonjans Kristina, Auwerx Johan, ;2011;Cell;147;827-39; 22078881
Homozygous fertile	not known
Homozygous viable	no
Homozygous matings required	no
Immunocompromised	not known

Information from EMMA

Archiving centre	ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Literature references

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.;Yamamoto Hiroyasu, Williams Evan G, Mouchiroud Laurent, Cantó Carles, Fan Weiwei, Downes Michael, Héligon Christophe, Barish Grant D, Desvergne Béatrice, Evans Ronald M, Schoonjans Kristina, Auwerx Johan, ;2011;Cell;147;827-39; 22078881

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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B6J.129S2-Ncor1tm1.2Ics/Ics