B6J.129S2-Nr5a1tm1.2Ics/Ics
| Status | Available to order |
| EMMA ID | EM:12984 |
| International strain name | B6J.129S2-Nr5a1tm1.2Ics/Ics |
| Alternative name | SF1 KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Nr5a1tm1.2Ics |
| Gene/Transgene symbol | Nr5a1 |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:not knownHeterozygous:not known |
| Breeding history | 7 backcross generations |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- 46,XX ovotesticular disorder of sex development / Orphanet_2138
- 46,XX testicular disorder of sex development / Orphanet_393
- Male infertility with azoospermia or oligozoospermia due to single gene mutation / Orphanet_399805
- 46,XY complete gonadal dysgenesis / Orphanet_242
- 46,XX gonadal dysgenesis / Orphanet_243
- 46,XY partial gonadal dysgenesis / Orphanet_251510