IMPC phenotypes (gene matching)
B6J.129S2-Nr2c2tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:12958 |
| Citation information | RRID:IMSR_EM:12958 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6J.129S2-Nr2c2tm1.1Ics/Ics |
| Alternative name | TR4 CM |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Nr2c2tm1.1Ics |
| Gene/Transgene symbol | Nr2c2 |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:NAHeterozygous:NA |
| Breeding history | 8 backcross generations |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased circulating LDL cholesterol level / MGI
- seminiferous tubule degeneration / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal eating behavior / MGI
- abnormal hemoglobin / MGI
- decreased inflammatory response / MGI
- reduced male fertility / MGI
- abnormal glucose homeostasis / MGI
- abnormal lipid homeostasis / MGI
- decreased susceptibility to hepatic steatosis / MGI
- decreased circulating triglyceride level / MGI
- oligozoospermia / MGI
- decreased circulating insulin level / MGI
- decreased circulating alanine transaminase level / MGI
- abnormal gas homeostasis / MGI
- decreased testis weight / MGI
- increased energy expenditure / MGI
- decreased circulating cholesterol level / MGI
- increased oxygen consumption / MGI
- abnormal energy homeostasis / MGI
- decreased circulating glucose level / MGI
- decreased circulating aspartate transaminase level / MGI
- decreased susceptibility to diet-induced obesity / MGI
- abnormal white adipose tissue physiology / MGI
- arrest of male meiosis / MGI
- increased carbon dioxide production / MGI
- decreased white fat cell size / MGI
- decreased abdominal fat pad weight / MGI
- decreased epididymal fat pad weight / MGI
- decreased liver triglyceride level / MGI
- abnormal blood homeostasis / MGI
- increased respiratory quotient / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- decreased body fat mass / MGI
- decreased brown adipose tissue mass / MGI
- multinucleated giant male germ cells / MGI