B6J.129S2-Rxrg^tm1.2Ics/Ics

Status	Available to order
EMMA ID	EM:12955
International strain name	B6J.129S2-Rxrg^tm1.2Ics/Ics
Alternative name	RXRg KO
Strain type	Targeted Mutant Strains : Knock-out
Allele/Transgene symbol	Rxrg^tm1.2Ics
Gene/Transgene symbol	Rxrg

Information from provider

Provider	ICS, Institut Clinique de la Souris
Provider affiliation	ICS, Institut Clinique de la Souris
Genetic information	For detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic information	Homozygous: https://www.mousephenotype.org/data/genes/MGI:98216 Heterozygous: https://www.mousephenotype.org/data/genes/MGI:98216
Breeding history	7 backcross generations
References	None available
Homozygous fertile	not known
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	not known

Information from EMMA

Archiving centre	ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)

decreased thermal nociceptive threshold / IMPC
increased circulating cholesterol level / IMPC
abnormal bone mineralization / IMPC
increased circulating HDL cholesterol level / IMPC
decreased grip strength / IMPC
increased circulating triglyceride level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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B6J.129S2-Rxrgtm1.2Ics/Ics