B6J.129S2-Nr1d2tm1.2Ics/Ics

Status

Available to order

EMMA IDEM:12933
International strain nameB6J.129S2-Nr1d2tm1.2Ics/Ics
Alternative nameRevErbb KO
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolNr1d2tm1.2Ics
Gene/Transgene symbolNr1d2

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
https://www.mousephenotype.org/data/genes/MGI:2449205

Heterozygous:
https://www.mousephenotype.org/data/genes/MGI:2449205
Breeding history7 backcross generations
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal iris morphology / IMPC
  • abnormal locomotor activation / IMPC
  • abnormal pupil morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • abnormal lens morphology / IMPC
  • increased B cell number / IMPC
  • decreased T cell number / IMPC
  • abnormal eye morphology / IMPC
  • cataract / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased startle reflex / IMPC
MGI phenotypes (gene matching)
  • abnormal heart morphology / MGI
  • increased anxiety-related response / MGI
  • no abnormal phenotype detected / MGI
  • no phenotypic analysis / MGI
  • impaired behavioral response to xenobiotic / MGI
  • ostium primum atrial septal defect / MGI
  • atrioventricular septal defect / MGI
  • inlet ventricular septal defect / MGI
  • common atrioventricular valve / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • preweaning lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).