IMPC phenotypes (gene matching)
B6J.129S2-Pparatm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:12930 |
| Citation information | RRID:IMSR_EM:12930 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6J.129S2-Pparatm1.1Ics/Ics |
| Alternative name | PPARa CM |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Pparatm1.1Ics |
| Gene/Transgene symbol | Ppara |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:NAHeterozygous:NA |
| Breeding history | 5 backcross generations |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Literature references
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.;Montagner Alexandra, Polizzi Arnaud, Fouché Edwin, Ducheix Simon, Lippi Yannick, Lasserre Frédéric, Barquissau Valentin, Régnier Marion, Lukowicz Céline, Benhamed Fadila, Iroz Alison, Bertrand-Michel Justine, Al Saati Talal, Cano Patricia, Mselli-Lakhal Laila, Mithieux Gilles, Rajas Fabienne, Lagarrigue Sandrine, Pineau Thierry, Loiseau Nicolas, Postic Catherine, Langin Dominique, Wahli Walter, Guillou Hervé, ;2016;Gut;65;1202-14; 26838599