C57BL/6NCrl-Pla2g5em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12856
International strain nameC57BL/6NCrl-Pla2g5em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPla2g5em1(IMPC)Ccpcz
Gene/Transgene symbolPla2g5

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • increased startle reflex / IMPC
  • abnormal lymph node morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • abnormal sinus arrhythmia / IMPC
  • increased eosinophil cell number / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • cardiovascular system phenotype / IMPC
IMPC phenotypes (gene matching)
  • small testis / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged lymph nodes / IMPC
  • increased startle reflex / IMPC
  • increased eosinophil cell number / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • enlarged spleen / IMPC
  • abnormal lymph node morphology / IMPC
  • abnormal testis morphology / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • abnormal sinus arrhythmia / IMPC
  • enlarged thymus / IMPC
  • cardiovascular system phenotype / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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